Prolia® may increase your risk of developing infections. Avoid being near people who are sick or have infections while you are receiving this medicine. Check with your doctor right away if you have a fever or chills, red, swollen skin, severe abdominal or stomach pain, or burning or painful urination.
People also ask, can Prolia affect your teeth?
Prolia may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, gum infection, or slow healing after dental work.
Likewise, people ask, do side effects of Prolia go away?
Some side effects from Prolia may last only a few days, while others may last several months. Because the drug can stay in your body for up to 6 months, some side effects can still occur months after your last dose of Prolia. This includes side effects that affect your teeth.
Does Prolia affect the heart?
Drug regulators in Australia are warning that the bone drugs Prolia and Xgeva, both of which use the active ingredient denosumab and are also available in the United States, could cause users to suffer abnormal heart rhythms linked to lowered calcium levels.
Does Prolia affect your kidneys?
Kidney function decline is not an adverse reaction that is listed in drug references for Prolia. However, this medication can cause a decrease in calcium (hypocalcemia), sometimes severely. The risk is greater with decreased kidney function, and health care providers are advised to use cautiously in these cases.
Does Prolia make a person gain weight?
Weight gain itself wasn’t reported as a side effect during clinical trials of Prolia. However, some people taking Prolia did have swelling in their arms or legs. And with swelling, your body weight can be quickly increased.
Does Prolia weaken your immune system?
Yes, Prolia (denosumab) does appear to weaken your immune system. Research has shown people who take Prolia are at an increased risk of serious infections leading to hospitalizations, including serious infections of the skin, abdominal, urinary tract, and ear.
How long can you stay on Prolia?
How long can I stay on Prolia for? For Prolia to work well at reducing fractures it needs to be taken long term and in one phase 2 clinical trial it has been used safely for up to 8 years with substantial increase in bone density, although most clinical trials are for 3 or 4 years.
Should I take calcium and Prolia with vitamin D?
You should take calcium and vitamin D as your doctor tells you to while you receive Prolia®. After your treatment with Prolia® is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased.
What are the dangers of Prolia?
Serious side effects that have been reported with Prolia include:
- severe bone, joint, or muscle pain.
- serious infections, including serious urinary tract infections or skin infections.
- unusual fractures in the thigh bone*
- decreased bone production (bones take longer to form new tissue)
What is the downside of taking Prolia?
Serious side effects of Prolia that have been reported include: serious infection, such as urinary tract infection (UTI) and skin infection. unusual bone fractures in your thigh. increased risk of bone fracture after stopping Prolia treatment, such as having multiple spine fractures.
What is the most common side effect of Prolia?
Bone pain. Pain, specifically musculoskeletal pain, is one of the most common side effects of Prolia.
What is the safest drug to take for osteoporosis?
Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.