In depressed patients using trazodone as an oral antidepressant several case reports have been pub- lished reporting uncommon sexual side-effects in- cluding penis elongation,1 orgasmic inhibition,2 spontaneous orgasms,3 clitoral priapism4 and in- creased libido.
Subsequently, does trazodone affect ability to orgasm?
Clinicians should be aware that trazodone may cause ejaculatory inhibition, understand that determination of sexual adverse effects necessitates directed and periodic questioning as these symptoms may increase in severity over time, and appreciate that religious patients may find discussing this issue difficult.
Correspondingly, does trazodone increase testosterone? Additionally, serum FSH, LH, and testosterone levels were elevated in the trazodone-administered groups. Increased MDA levels were the signs of enhanced oxidative stress after trazodone administration in testis tissues.