Because EDS is a connective-tissue disorder, it is not commonly associated with the brain or the nervous system. However, there is evidence that some types of EDS can affect the brain. Studies have suggested that patients with EDS might be susceptible to damage to brain cells after even a mild traumatic head injury.
Thereof, can EDS cause brain lesions?
Patients with EDS, hypermobility type, were found to have consistent and specific brain lesions involving white matter tracts. Moreover, the record of a physical trauma in a substantial proportion of cases suggests that these lesions could be post-trauma consequences.
Keeping this in view, can Ehlers-Danlos cause brain aneurysm?
Objective: Ehlers-Danlos syndrome Type IV is a heritable connective tissue disorder with frequent neurovascular manifestations, such as intracranial aneurysms. Patients with this syndrome have notoriously fragile blood vessels, and the reported mortality rate for any type of vascular surgical procedure is 40%.
Can Ehlers-Danlos cause dementia?
Participants with 1 EDS had an 87% increased risk of developing dementia, while those with 2 or more EDS were nearly twice as likely to develop dementia. Cox proportional hazards models showed a 14% increase in dementia risk with each occurrence of an EDS.
Does EDS cause memory loss?
While “brain fog” is not one of the most common symptoms of Ehlers-Danlos syndrome (EDS), many patients report experiencing this form of cognitive dysfunction, which can affect their ability to focus, learn, retain information, and maintain employment.
Does EDS get worse with age?
Many of the problems associated with EDS are progressive, meaning that they get worse over time.
Does EDS show on MRI?
MRI can help detect lesions in the brain containing collagen fibers, which are often seen in EDS patients who previously experienced trauma.
Does Ehlers-Danlos affect mental health?
Psychiatric disorders were found in 42.5% of the EDS cohort, with 22.7% of patients affected with 2 or more psychiatric diagnoses. Anxiety and depression were most commonly reported, with frequencies of 23.6 and 25.5%, respectively. A variety of other psychiatric diagnoses were also identified.
Does hypermobility affect the brain?
An evolving body of scientific work links joint hypermobility to symptoms in the brain, notably anxiety and panic. If you suffer with anxiety or have a panic attack you are considerably more likely than chance to also have hypermobile joints.
Does magnesium help EDS?
This can be very helpful for our patients with EDS/HSD, since many report difficulty falling and staying asleep. In addition , magnesium is involved in hundreds of biochemical reactions in your body. It aids in energy creation, protein formation, gene maintenance, muscle movements, and nervous system regulation.
Is Ehlers-Danlos neurological?
Although the nervous system is not considered a primary target of the underlying molecular defect, recently, increasing attention has been posed on neurological manifestations of EDSs, such as musculoskeletal pain, fatigue, headache, muscle weakness and paresthesias.
What is fuzzy brain?
What is brain fog? While it’s not a medical term, brain fog describes a feeling that you don’t have full mental clarity—maybe you’re having trouble remembering something or difficulty focusing on a thought or idea.
What mimics Ehlers-Danlos syndrome?
Tnxb−/− mice showed progressive skin hyperextensibility, similar to individuals with Ehlers–Danlos syndrome. Biomechanical testing confirmed increased deformability and reduced tensile strength of their skin.
Why does EDS cause brain fog?
In hEDS/HSD, it is thought that brain fog may be related to lack of blood flow to the brain due to blood pooling in the legs because of stretchy veins.