Symptoms of CF
Frequent lung infections including pneumonia Inflammation of the lungs often caused by a bacterial or viral infection. or bronchitis. Wheezing or shortness of breath. Poor growth or weight gain in spite of a good appetite. Frequent greasy, bulky stools or difficulty with bowel movements.
Considering this, how does cystic fibrosis affect the circulatory system?
Available evidence indicates that cystic fibrosis causes widespread involvement of the cardiovascular system. Aside from the heart, unusual aberrations have been observed in the bronchial arteries, the aorta, and the systemic capillaries. Of all cardiovascular complications, cor pulmonale is the most serious.
Correspondingly, what are the physiological effects of cystic fibrosis?
CF causes thick mucus that clogs certain organs, such as the lungs, pancreas, and intestines. This may cause malnutrition, poor growth, frequent respiratory infections, breathing problems, and chronic lung disease.
What are the primary nursing interventions in the management of respiratory distress in cystic fibrosis?
Nursing Interventions
- Improve airway clearance. …
- Improve breathing. …
- Prevent infection. …
- Maintain adequate nutrition. …
- Reducing the child’s anxiety. …
- Provide family support.
What are the signs of cystic fibrosis in babies?
If your baby does have CF, they may have these signs and symptoms that can be mild or serious:
- Coughing or wheezing.
- Having lots of mucus in the lungs.
- Many lung infections, such as pneumonia and bronchitis.
- Shortness of breath.
- Salty skin.
- Slow growth, even with a big appetite.
What are the symptoms of cystic fibrosis in adults?
Symptoms for Cystic Fibrosis in Adults
- A persistent cough.
- Wheezing.
- Lung infections.
- Pancreatitis (inflammation of the pancreas)
- Sinusitis.
- Malnutrition.
- Infertility.
- Arthritis.
What is the earliest clinical manifestation of cystic fibrosis?
Early signs of CF include:
- Salty sweat; many parents notice a salty taste when kissing their child.
- Poor growth and weight gain (failure to thrive)
- Constant coughing and wheezing.
- Thick mucus or phlegm.
- Greasy, smelly stools that are bulky and pale colored.
What is the most common complication of cystic fibrosis?
The most common complication is chronic respiratory infection. Other complications include: Bowel problems, such as gallstones, intestinal blockage, and rectal prolapse.
What organelle is affected by cystic fibrosis?
In most kids with cystic fibrosis, says Balch, the CFTR protein gets stuck inside the cells in a cell organelle known as the endoplasmic reticulum—a convoluted membranous sac within the cell where the synthesis of proteins like CFTR and other vital cell functions take place.
What other clinical features would suggest pneumonia?
Signs and symptoms of pneumonia may include:
- Chest pain when you breathe or cough.
- Confusion or changes in mental awareness (in adults age 65 and older)
- Cough, which may produce phlegm.
- Fatigue.
- Fever, sweating and shaking chills.
Which of the following are potential complications of cystic fibrosis?
The following are potential complications of cystic fibrosis:
- Nasal polyps.
- Chronic and persistent sinusitis with complications such as mucopyocele formation.
- Bronchiectasis.
- Atelectasis.
- Pneumothorax.
- Hemoptysis.
- Hypertrophic pulmonary osteoarthropathy.
- Allergic bronchopulmonary aspergillosis (ABPA)
Which primary factor is responsible for multiple clinical manifestations of cystic fibrosis?
Results. Cystic fibrosis is caused by a gene mutation leading to dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It affects multiple organ systems—the lungs, pancreas, upper airways, liver, intestine, and reproductive organs—to varying degrees.
Who does cystic fibrosis affect the most?
The most affected group is Caucasians of northern European ancestry. About 30,000 people in the United States have cystic fibrosis. The disease affects about 1 in 2,500 to 3,500 white newborns. It’s not as common in other ethnic groups.
Why is immunoreactive Trypsinogen elevated in CF?
The concentration of IRT is elevated in babies with CF since pancreatic ducts are partially blocked leading to abnormal enzyme drainage. Heterozygous carriers of cystic fibrosis can cause a raised IRT and it is therefore not diagnostic in isolation.