How common are false-positive TB tests?

In 18 studies involving 1,169,105 subjects, the absolute prevalence of false-positive TST from NTM cross-reactivity ranged from 0.1% to 2.3% in different regions. Conclusions: The effect on TST of BCG received in infancy is minimal, especially > or =10 years after vaccination.

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Additionally, can you test positive for TB and not have it?

Persons with latent TB infection (LTBI) do not feel sick and do not have any symptoms, but usually have a positive reaction to the tuberculin skin test or TB blood test. They are infected with TB bacteria, but do not have TB disease.

One may also ask, what can cause a false-positive TB Gold test? (1) False-positive results may occur in patients with prior infection with M marinum, M szulgai, or M kansasii. Negative: No IFN-gamma response to M tuberculosis antigens was detected. Infection with M tuberculosis is unlikely.

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