The traditional drug of choice for therapy of hypertensive emergencies is sodium nitroprusside. Intravenous labetalol produces a prompt, controlled reduction in blood pressure and is a promising alternative. Other agents used are diazoxide, trimethaphan camsylate, hydralazine, nitroglycerin, and phentolamine.
Just so, what is a thiazide diuretic drug?
Thiazide diuretics are an FDA-approved class of drugs that inhibit the reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. By doing so, thiazide diuretics promote natriuresis and diuresis.
Then, why is nicardipine used in hypertensive emergency?
PHOENIX, ARIZ. — Intravenous nicardipine can reduce blood pressure by 15%–20% without impairing blood supply to the brain in hypertensive emergencies, preliminary results from an ongoing case-control study suggest.